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Mounjaro (tirzepatide) is a once-weekly injectable medication that mimics the effects of two hormones: GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide). These hormones help regulate blood sugar levels, control appetite, and improve insulin sensitivity.
Mounjaro is licensed in the UK for type 2 diabetes but is increasingly being used off-label for weight loss under the supervision of qualified healthcare professionals.
Mounjaro may be suitable for you if:
You are aged 18 or over
You have a BMI of 30 or higher, or 27+ with weight-related conditions (e.g., high blood pressure, PCOS)
You are committed to lifestyle changes, including diet and exercise
A consultation with a prescribing clinician is required to assess suitability and rule out any contraindications.
Mounjaro is administered as a once-weekly injection, typically in the abdomen or thigh. Patients usually start on a low dose (e.g. 2.5mg) and gradually increase to a higher maintenance dose over several weeks.
Your prescriber will create a personalised treatment plan based on your progress and response.
Month 1: Your body adjusts to the medication. Appetite begins to reduce.
Month 2–3: Noticeable weight loss and reduced portion sizes.
Month 4+: Weight loss continues steadily, especially with diet/exercise support.
Results vary, but consistency and follow-up are key to long-term success.
Common side effects include:
Nausea or upset stomach (often temporary)
Constipation or diarrhoea
Fatigue
Injection site irritation
Most symptoms improve as your body adjusts. Always report side effects to your prescriber.
Q: Is Mounjaro the same as Ozempic or Wegovy?
A: No – Mounjaro contains tirzepatide, whereas Ozempic and Wegovy contain semaglutide. Mounjaro targets two receptors (GLP-1 and GIP), making it potentially more effective.
Q: How much weight will I lose on Mounjaro?
A: Many patients lose between 10–20% of their body weight, but results depend on individual response, dosage, and lifestyle.