Overview
Nytol Original 25mg is a trusted short-term sleep aid designed to help relieve temporary sleep disturbance and promote a natural, restful night’s sleep. It contains diphenhydramine, an antihistamine with sedating properties that works by reducing alertness and encouraging drowsiness, helping you relax and drift off more easily at bedtime.
Nytol Original is ideal for those experiencing occasional difficulty falling asleep due to everyday factors such as stress, jet lag, or changes to routine. With a lower strength than one-a-night formulations, it offers a gentle yet effective option for night-time use when you need support settling into sleep. It does not treat underlying sleep disorders and should be used for short periods only.
Suitable for adults and adolescents aged 16 years and over, Nytol Original 25mg helps support a more refreshing night’s sleep so you wake feeling rested and ready for the day ahead.
Directions
- For oral use only.
Swallow the tablet whole with water.
Take shortly before bedtime.
Adults and adolescents aged 16 years and over:
Take one tablet (25mg) at bedtime.
Do not take more than one tablet in any 24-hour period.
Children under 16 years:
Not suitable.
Do not use for more than 7 consecutive nights without consulting a doctor or pharmacist.
Side Effects
Like all medicines, Nytol Original can have side effects, although not everybody gets them.
The most common side effects (may affect up to 1 in 10 people) are:
- Tiredness
- Drowsiness
- Reduced attention
- Unsteadiness
- Dizziness
- Dry mouth.
Not known (frequency cannot be estimated from the available data)
- Allergic reactions (such as rash, shortness of breath and swelling), blurred vision,
palpitations (feeling your heartbeat) or irregular heartbeat. - Muscle twitching, convulsions, headache or pins and needles.
- Also nausea (feeling sick), vomiting (being sick), thicker bronchial mucus and difficulty
passing urine.
Warnings
Do not take Nytol Original:
- If you have ever had an allergic reaction to diphenhydramine hydrochloride or any of the other
ingredients - If you have an obstruction in your stomach or gut (for example, because of an ulcer).
Warnings and precautions
Talk to your doctor or pharmacist before taking Nytol Original:
- If you have asthma, bronchitis or Chronic Obstructive Pulmonary Disease (COPD)
- If you have narrow-angle glaucoma (a form of raised pressure in the eye)
- If you have an enlarged prostate or urinary retention
- If you have moderate to severe liver or kidney disease
- If you have myasthenia gravis, epilepsy or seizure disorders.
- If your sleeping difficulties persist, talk to your doctor or pharmacist.
Other medicines and Nytol Original:
Talk to your doctor or pharmacist before taking these tablets if you are taking any prescribed medicines; particularly tricyclic antidepressants, monoamine oxidase inhibitors (MAOIs prescribed for depression) within the last two weeks, atropine (used to dilate pupils of the eyes) or medicines which make you drowsy. Avoid the use of other antihistamines including those used on your skin and in cold and cough medicines, while taking this medicine. Do not drink alcohol while using Nytol One-A-Night.
Do not drive or operate machinery. Nytol Original is intended to produce sleepiness or drowsiness soon after the dose is taken.
Nytol Original may get less effective if you use it continuously.
Ingredients
Active ingredients: each tablet contains diphenhydramine hydrochloride 25 mg.
Other ingredients: anhydrous lactose, microcrystalline cellulose, maize starch, stearic acid and silicon dioxide.
FAQ
What is Nytol?
Nytol One a Night is an antihistamine medicine which helps the patient relax and to fall asleep, it is
shown to increase early drowsiness helping to ease the patient into a restful and deeper sleep.
Is Nytol right for me?
Nytol One a Night is suitable for those who suffer from short term insomnia. You should not take
this medication if any of the warnings in the information leaflet apply to you.
How does Nytol work?
Nytol One-A-night tablets is an antihistamine medicine, this means when a tablet is taken it blocks
the normal actions of histamine which stop making the brain aroused. Each tablet contains 50mg of
diphenhydramine hydrochloride, this helps to reduce alertness and helping you to fall into the first
drowsy stage of sleep allowing the patient to have restful and deeper sleep.
Can I drink alcohol if I take Nytol?
No. If you take Nytol you cannot drink alcohol whilst taking this medication.
Can I drive/operate machinery if I have taken Nytol?
No. You cannot drive or operate machinery if you have taken Nytol as the purpose of the medication
is to cause drowsiness in order to aid sleep.
Can I take Nytol if I am pregnant or breastfeeding?
No. If you are pregnant or breastfeeding it is advised that you speak to your own GP.
